Every time you open a new scene, use Forensic to inspect the scene integrity, modifiers, plugins and quickly fix any problems before getting started.
Working on a bad scene will likely cause you issues. Some typical issues might be; 3ds Max Viruses, empty objects crashing, drawn-out simulation times, cad blocks and linked composites clogging up scenes, 3rd-party plugin mismatches e.g, Vray planes not rendering with Arnold and Corona lights.
3ds Max viruses or malicious MAXScripts will cause havoc with your scene if infected. Forensic will find these and give you the option to delete. You can also switch on Add Virus Callback from the SiNi Dropdown to automatically delete all known viruses on file open.